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Both the SH2 and SH3 domains of human CRK protein are required for neuronal differentiation of PC12 cells.
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Tanaka, S., Morishita, T., Hashimoto, Y., Hattori, S., Nakamura, S., Shibuya, M., Matsuoka, K., Takenawa, T., Kurata, T., Nagashima, K., and Matsuda, M.
C3G, a Guanine Nucleotide Releasing Protein Expressed Ubiquitously, Binds to the SH3 domain of CRK and GRB2/ASH.
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Tanaka, S., Ouchi, T., and Hanafusa, H.
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Guanine-nucleotide exchange protein C3G activates JNK1 by a Ras-independent mechanism: JNK1 activation inhibited by kinse negative forms of MLK3 and DLK mixed lineage kinases.
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Analysis of transforming activity of human synovial sarcoma-associated chimeric protein SYT-SSX1 bound to chromatin remodeling factor hBRM/hSNF2α
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Nishihara, H., Maeda, M., Oda, A., Tsuda, M., Sawa, H., Nagashima, K, and Tanaka, S.
DOCK2 associates with CrkL and regulates Rac1 in hematopoietic cells.
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Tsuda, M., Makino Y., Iwahara, T., Nishihara, H., Sawa, H., Nagashima, K., Hanafusa, H., and Tanaka, S.
Crk associates with ERM proteins and promotes cell motility towards hyaluronic acid.
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Tsuda, M., Watanabe, T., Seki, T., Kimura, T., Sawa, H., Minami, A., Akagi, T., Isobe, K., Nagashima, K., and Tanaka, S.
Human synovial sarcoma chimeric oncogene product SYT-SSX1 induces premature senescence.
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Linghu, H., Tsuda, M., Makino, Y., Sakai, M., Watanabe,, T., Ichihara, S., Sawa, H., Nagashima, K. Mochizuki, N., and Tanaka, S.
Involvement of adaptor protein Crk in malignant feature of human ovarian cancer cell line MCAS.
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Kobashikawa, Y., Sakai, M., Naito, M., Yokochi, M., Kumeta, H., Makino, Y., Ogura, K., *Tanaka, S., and *Inagaki,F. (*co-corresponding author)
Structural basis for the transforming activity of human cancer-related signaling adaptor protein CRK
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Sasai, K., Nodagashira, M., Nishihara, H., Aoyanagi, E., Wang, L., Katoh, M., Murata, J., Ozaki, Y., Ito, T., Fujimoto, S., Kaneko, S., Nagashima, K., and Tanaka, S.
Careful exclusion of non-neoplastic brain components is required for an appropriate evaluation of MGMT status in glioma.
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Tabu, K., Kimura, T., Sasai, K., Wang, L., Bizen, N., Nishihara, H., Taga, T., Tanaka, S.
Analysis of an alternative human CD133 promoter reveals the implication of Ras/ERK pathway in tumor stem-like hallmarks.
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STAT3 inhibition overcomes temozolomide resistance in glioblastoma by downregulating MGMT expression.
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Sustained elevation of Snail promotes glial-mesenchymal transition after irradiation in malignant glioma.
Neuro Oncol., 5, 671-685, 2014.
