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論文　2012年

Original Article

  1. Kohsaka, S., Wang, L.,.Yachi, K.,.Mahabir, R.,.Narita, T.,.Itoh, T.,Tanino, M.,.Kimura, T.,.Nishihara H.,.and Tanaka, S. STAT3 inhibition overcomes temozolomide resistance in glioblastoma by downregulating MGMT expression. Mol. Cancer. Ther., 11, 1289-1299, 2012.　
  2. Kimura, T., Wang, L., Tabu, K., Nishihara, H., Mashita, Y., Kikuchi, N., Tanino, M., Hiraga, H., and Tanaka, S. CD133 negatively regulates tumorigenicity via AKT pathway in synovial sarcoma. Cancer invest., 30, 390-397, 2012.　
  3. Kanno, H., Nishihara, H., Narita, T., Yamaguchi, S., Kobayashi, H., Tanino, M., Kimura, T., Terasaka S., and Tanaka, S. Prognostic implication of histological oligodendroglial tumor component: clinicopathological analysis of 111 cases of malignant gliomas. PLoS One, 7, e41669, 2012.　
  4. Yanagi, H., Wang , L., Nishihara, H., Kimura, T., Tanino, M., Yanagi, T., Fukuda, S., and Tanaka, S. CRKL plays a pivotal role in tumorigenesis of head and neck squamous cell carcinoma through the regulation of cell adhesion. Biochem. Biophys. Res. Commun., 418, 104-109, 2012.　
  5. Kanno, H., Nishihara, H., Oikawa, M., Ozaki, Y., Murata, J., Sawamura, Y., Kato, M.., Kubota, K., Tanino, M., Kimura, T., Nagashima, K., Itoh, T., and Tanaka, S. Expression of O6-methylguanine DNA methyltransferase (MGMT) and immunohistochemical analysis of 12 pineal parenchymal tumors. Neuropathol., 32, 647-653, 2012.　
  6. Saito, M.,Nishihara, H.,Tanino, M.,Kimura, T.,Matsuno, Y.,Nagashima, K.,Shimizu, M., and Tanaka, S. Pancreatic carcinoma with prominent mucin production: A clinicopathologic and immunohistochemical study of 9 cases. Open Journal of Pathol., 2, 12-20, 2012.
  7. Shime, H., Matsumoto, M., Oshiumi, H., Tanaka, S., Nakane, A., Iwakura, Y., Tahara, H., Inoue, N., and Seya, T. Toll-like receptor 3 signaling converts tumor-supporting myeloid cells to tumoricidal effectors. Proc. Natl. Acad. Sci. USA, 109, 2066-2071, 2012.　
  8. Yaguchi, H., Okumura, F., Takahashi, H., Kano, T., Kameda, H., Uchigashima, M., Tanaka, S., Watanabe, M., Sasaki, H., and Hatakeyama, S. TRIM67 negatively regulates Ras activity through degradation of 80K-H and induces neuritogenesis. J. Biol. Chem., 287, 12050-12059, 2012.　
  9. Nakajima, N., Sato, Y.,Katano, H., Hasegawa, H., Kumasaka, T., Hata, S., Tanaka, S., Amano, T.,Kasai, T., Chong, J.M., Iiduka, T., Nakazato, I., Hino, Y., Hamamatsu, A., Horiguchi, H., Tanaka, T., Hasagawa, A., Kanaya, Y., Oku, R., Oya, T., and Sata, T. Histopathological and immunohistochemical findings of 20 autopsy cases with 2009 H1N1 virus infection. Mod. Pathol., 25, 1-13, 2012.　
  10. Tsukiyama, T., Matsuda-Tsukiyama, M., Bohgaki, M., Terai, S., Tanaka, S., and Hatakeyama, S. Ymer acts as a multifunctional regulator in NF-κB and Fas signaling pathways. Mol. Med., 18, 587-597, 2012.　
  11. Watari, H., Kinoshita, R., Han, Y., Wang, L., Hosaka, M., Taguchi, H. ,Tsuchiya, K., Tanaka, S., Shirato, H., and Sakuragi, N. Prognostic Significance of Clusterin Expression in Advanced-Stage Cervical Cancer Treated With Curative Intended Radiotherapy. Int. J. Gynecol. Cancer, 22, 465-470, 2012.　
  12. Hirata, K., Terasaka, S., Shiga, T., Hattori, N., Magota, K., Kobayashi, H., Yamaguchi, S., Houkin, K., Tanaka, S., Kuge, Y., and Tamaki, N. 18F-fluoromisonidazole positron emission tomography may differentiate glioblastoma multiforme from less malignant gliomas. Eur. J. Nucl. Med. Mol. Imaging, 39,760-770, 2012.　
  13. Muraki, C., Ohga, N., Hida, Y., Nishihara, H., Kato, Y., Tsuchiya, K., Matsuda, K., Totsuka, Y., Shindoh, M., and Hida, K. Cyclooxygenase-2 inhibition causes antiangiogenic effects on tumor endothelial and vascular progenitor cells. Int. J. Cancer, 130, 59-70, 2012.　
  14. Matsukawa, T., Goto, H., Takahashi, K., Asanuma, S., Yasumoto, A., Takahata, M., Shigematsu, A., Endo, T., Tanaka, J., Hashino, S., Tanaka, S., and Imamura, M. A fatal case of cytomegalovirus ventriculoencephalitis in a mycosis fungoides patient who received multiple umbilical cord blood cell transplantations. Int. J. Hematol., 95, 217-222, 2012.　
  15. Narita, T., Aoyama, H., Hirata, K., Onodera, S., Shiga, T., Kobayashi, H., Murata, J., Terasaka, S., Tanaka, S., and Houkin, K. Reoxygenation of Glioblastoma Multiforme Treated with Fractionated Radiotherapy Concomitant with Temozolomide: Changes Defined by 18F-fluoromisonidazole Positron Emission Tomography: Two Case Reports. Jpn. J. Clin. Oncol., 42, 120-123, 2012.　
  16. Yamaguchi, S., Kobayashi, H., Terasaka, S., Ishii, N., Ikeda, J., Kanno, H., Nishihara, H., Tanaka, S., and Houkin, K. The Impact of Extent of Resection and Histological Subtype on the Outcome of Adult Patients with High-grade Gliomas. Jpn. J. Clin. Oncol., 420, 270-277, 2012.　
  17. Einama, T., Homma, S., Kamachi, H., Kawamata, F., Takahashi, K., Takahashi, N., Taniguchi, M., Kamiyama, T., Furukawa, H., Matsuno, Y., Tanaka, S., Nishihara, H. ,Taketomi, A., and Todo, S. Luminal membrane expression of mesothelin is a prominent poor prognostic factor for gastric cancer. Br. J. Cancer, 107, 137-142, 2012.　
  18. Arai ,R., Tsuda, M., Watanabe, T., Ose, T., Obuse, C., Maenaka, K., Minami, A., and Ohba, Y. Simultaneous inhibition of Src and Aurora kinases by SU6656 induces therapeutic synergy in human synovial sarcoma growth, invasion and angiogenesis in vivo. Eur. J. Cancer, 48, 2417-2430, 2012.　
  19. Wakayama, K., Fukai, M., Yamashita, K., Kimura, T., Hirokata, G., Shibasaki, S., Fukumori, D., Haga, S., Sugawara, M., Suzuki, T., Taniguchi, M., Shimamura, T., Furukawa, H., Ozaki, M., Kamiyama, T. and ,Todo, S. Successful transplantation of rat hearts subjected to extended cold preservation with a novel preservation solution. Transpl. Int., 25, 696-706, 2012.　
  20. Hosoya, H., Kadowaki, K., Matsusaki, M., Cabral, H., Nishihara, H., Ijichi, H., Koike, K., Kataoka, K., Miyazono, K., Akashi, M., and Kano, M.R.. Engineering fibrotic tissue in pancreatic cancer: A novel three-dimensional model to investigate nanoparticle delivery. Biochem. Biophys. Res. Commun., 419, 32-37, 2012.　
  21. Yuzawa S, Kano MR, Einama T, and Nishihara H. PDGFRβ expression in tumor stroma of pancreatic adenocarcinoma as a reliable prognostic marker. Med. Oncol., 29, 2824-2830, 2012.　
  22. Zhang, L., Nishihara, H., and Kano, M.R.. Pericyte-coverage of human tumor vasculature and nanoparticle permeability. Biol. Pharm. Bull., 35, 761-6, 2012.
  23. Kawamata, F., Kamachi, H., Einama, T., Homma, S., Tahara, M., Miyazaki, M., Tanaka, S., Kamiyama, T., *Nishihara, H., Taketomi, A., and Todo, S.. Intracellular localization of mesothelin predicts patient prognosis of extrahepatic bile duct cancer. Int. J. Oncol., 41, 2109-2118, 2012.　
  24. 鴨嶋雄大、茂木洋晃、寺坂俊介、小林浩之、山口秀、村田純一、田中伸哉、寳金清博　膠芽腫患者長期生存5例の検討─特にIDH1遺伝子変異，MGMT遺伝子プロモーターメチル化に関して脳神経外科, 40, 129-135, 2012.

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Case Report

  1. Tanino, M., Kohsaka, S., Kimura, T., Tabu, K., Nishihara, H., Sawa, H., Kawami, H., Kamada, H., Shimizu, M., and Tanaka, S. A case of clear cell variant of solid-pseudopapillary tumor of the pancreas in an adult male patient. Ann. Diagn. Pathol., 16, 134-140, 2012.　
  2. Terasaka, S., Kawabori, M., Kobayashi, H., Murata, J., Kanno, H., Tanaka, S., and Houkin, K. Neurohypophyseal germinoma with abundant fibrous tissue.Brain Tumor Pathol., 29, 58-62, 2012.　
  3. Matsukawa, T.,Goto, H., Takahashi, K., Asanuma, S., Yasumoto, A., Takahata, M., Shigematsu, A., Endo, T.. Tanaka, J., Hashino, S., and Tanaka, S., Imamura, M.A fatal case of cytomegalovirus ventriculoencephalitis in a mycosis fungoides patient who received multiple umbilical cord blood cell transplantations. Int. J. Hematol., 95, 217-222, 2012.　
  4. Kamoshima, Y., Terasaka, S., Kobayashi, H., Kaneko, S., Kubota, K., Tanaka, S., and Houkin, K. Radiation induced intraparenchymal meningioma occurring 6 years after CNS germinoma: case report. Clin. Neurol. Neurosurg., 114, 1077-1080, 2012.　
  5. Saito, M., Morioka, M., Kanno, H., and Tanaka, S. Acute phlegmonous gastritis with neutropenia. Intern. Med., 51, 2987-2988, 2012.
  6. 姜貞憲、瀧山晃弘、桜井康雄、松居剛志、金俊文、志田勇人、辻邦彦、児玉芳尚、安保義恭、篠原敏也、真口宏介. 肝細胞癌を合併した非線維化NASH 及び遺伝子型Ae HBV 起因B 型慢性肝炎の1 例 肝臓, 53 巻2号, 90-100, 2012.
  7. 笹木有佑、高野眞寿、谷野美智枝、露口雅子、長佐古友和、川村直之、工藤峰生、土橋誠一郎、飯田潤一. くり返す出血のために腸管切除を必要とした長期血液透析患者の特発性腸間膜静脈硬化症の１例. Gastroenterological Endoscopy, 54巻7号, 2039-2045, 2012.

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Review, etc.

  1. Shinya Tanaka. “CRK”
    Atlas of Genetics and Cytogenetics in Oncology and Haematology 2012.
  2. Masumi Tsuda, Shinya Tanaka. Roles for Crk in cancer metastasis and invasion.
    Genes Cancer.,     334-340, 2012.　
  3. Tsuda, M., Ohba, Y. Functional Biomarkers of Oral Cancer.
    Oral Cancer.     Chapter 15, 2012 ISBN 978-953-307-805-2.　
  4. Ohba, Y., Darmanin, S., Mizutani, T., Tsuda, M., and Kondo, T. Biosensors for BCR-ABL activity and their application to cancer.
    Biosensors and Cancer, Chapter14, 268-283, 2012.
  5. 大場雄介, 津田真寿美. 細胞内シグナル伝達の可視化技術と分子標的治療薬の耐性判定への応用
    生化学 84巻, 359-365, 2012
  6. 高阪真路、菅野宏美、田中伸哉. 分子標的薬耐性化メカニズムの解明 グリオーマにおけるMGMTの発現調節と抗がん剤耐性解除を目指した治療への応用.
    日本臨床     70巻, 346-352, 2012.
  7. 田中伸哉　毛様体性星細胞腫におけるBRAFの遺伝子異常　
    病理と臨床, 30, 380-385, 2012.
  8. 田中伸哉 はじめの一歩のイラスト病理学 第1章、第9章　羊土社、2012
 

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